866890-75-7

Upstream product

• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 1030614-10-8 (3aR,5R,6S,6aR)-[6-(2-bromo-5-methoxybenzyloxy)-2,2-dimethyltetrahydro-2H-furo[2,3-d][1,3]dioxol-5-yl]methanol 
• 200346-53-8 (3aR,5R,6S,6aR)-6-(2-bromo-5-methoxybenzyloxy)-5-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydro-2H-furo[2,3-d][1,3]dioxole 
• 200346-55-0 (R)-1-[(3aR,5R,6S,6aR)-6-(2-Bromo-5-methoxy-benzyloxy)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl]-ethane-1,2-diol 
• 19614-12-1 2-bromo-5-methoxybenzyl bromide 

Downstream Products

• 866890-78-0 (3aR,6R,6aR)-6-(2-bromo-5-methoxy-benzyloxy)-2,2-dimethyl-5-methylene-tetrahydro-furo[2,3-d][1,3]dioxole 

Relevant academic research and scientific papers

Radical cyclization of exo-methylene furanose derivatives: An expedient approach to the synthesis of chiral tricyclic nucleosides and benzannulated oxepine derivatives

Tributyltin radical mediated cyclization of the glucose derived exo-methylene furanose derivatives 5a-c led to the highly functionalized cis-fused bicyclic ethers 6a-c. The product could subsequently be transformed to the optically active tricyclic nucleoside analogue 8 or oxepine derivative 9.