866923-64-0 Usage
Uses
Used in Pharmaceutical Industry:
Thiomethyl Cyclopropyl Acetonitrile is used as a key reagent in the synthesis of Montelukast Sodium Salt (M568000), a selective leukotriene D4-receptor antagonist. Thiomethyl Cyclopropyl Acetonitrile plays a significant role in the development of antiasthmatic medications, as it helps in the production of Montelukast, which is effective in treating asthma and other respiratory conditions by blocking the action of leukotriene D4, a potent inflammatory mediator.
Check Digit Verification of cas no
The CAS Registry Mumber 866923-64-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,6,9,2 and 3 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 866923-64:
(8*8)+(7*6)+(6*6)+(5*9)+(4*2)+(3*3)+(2*6)+(1*4)=220
220 % 10 = 0
So 866923-64-0 is a valid CAS Registry Number.
866923-64-0Relevant academic research and scientific papers
PREPARATION OF MONTELUKAST AND ITS SALTS
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Page/Page column 37-38, (2008/12/05)
There is provided a process for the preparation of montelukast of the Formula (I).
Process for the preparation of [R-(E)-1-[[[1-[3-[2-[7-chloro-2-quinolinyl]ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid (montelukast) and its pharmaceutically acceptable salts
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Page/Page column 5, (2010/02/14)
The present invention is related to a process for preparing montelukast involving the compound of formula (VI): wherein X═CN or CONH2.
