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Usage

Uses

Used in Pharmaceutical Industry:
N-[3,5-bis(trifluoromethyl)phenyl]-N'-[(1R)-2'-(dimethylamino)[1,1'-binaphthalen]-2-yl]Thiourea is utilized as a pharmaceutical candidate for its potential therapeutic applications. N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1R)-2'-(diMethylaMino)[1,1'-binaphthalen]-2-yl]Thiourea's unique structure and functional groups may contribute to its interaction with biological targets, such as enzymes or receptors, and could be explored for the development of new drugs with specific therapeutic effects.
Used in Chemical Research:
In the field of chemical research, N-[3,5-bis(trifluoromethyl)phenyl]-N'-[(1R)-2'-(dimethylamino)[1,1'-binaphthalen]-2-yl]Thiourea serves as a valuable subject for studying the properties and reactivity of complex organic molecules. Its diverse functional groups and structural features provide opportunities for investigating various chemical reactions and mechanisms, contributing to the advancement of organic chemistry.
Used in Material Science:
N-[3,5-bis(trifluoromethyl)phenyl]-N'-[(1R)-2'-(dimethylamino)[1,1'-binaphthalen]-2-yl]Thiourea may also find applications in material science, where its unique molecular structure could be leveraged to develop new materials with specific properties. N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1R)-2'-(diMethylaMino)[1,1'-binaphthalen]-2-yl]Thiourea's aromatic and aliphatic components, along with its functional groups, could be explored for the creation of novel materials with applications in various industries, such as electronics, coatings, or adhesives.

Upstream product

• 23165-29-9 3,5-bistrifluoromethylphenylisothiocyanate 

Relevant academic research and scientific papers

NEW PROCESS

The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril. It further relates to new intermediate compounds and their use for said new chemical synthesis

Organocatalysts and methods of use in chemical synthesis

The present invention is directed to compositions comprising organocatalysts that facilitate stereo-selective reactions and the method of their synthesis and use. Particularly, the invention relates to metal-free organocatalysts for facilitation of stereo

A novel bis-thiourea organocatalyst for the asymmetric aza-Henry reaction

A novel bis-thiourea/2,2′-diaminobinaphthalene (BINAM)-based catalyst for the asymmetric aza-Henry reaction has been developed. This catalyst promotes the reaction of N-Boc imines with nitroalkanes to afford β-nitroamines with good yields and high enantioselectivities. This catalyst has the advantage that it can be prepared in a single step from commercially available materials. A model is proposed for the catalyst action where both components of the reaction are activated simultaneously by hydrogen bonding. Regardless of the mechanism, the success of the present catalyst demonstrates the potential of bis-thioureas as an interesting class of relatively unexplored catalysts.

Chiral binaphthyl-derived amine-thiourea organocatalyst-promoted asymmetric Morita-Baylis-Hillman reaction

(Chemical Equation Presented) A new bifunctional binaphthyl-derived amine thiourea organocatalyst has been developed to promote enantioselective Morita-Baylis-Hillman reaction of cyclohexenone with a wide range of aldehydes. The process, catalyzed by the

Organocatalytic asymmetric michael addition of 2,4-pentandione to nitroolefins

(Chemical Equation Presented) A novel binaphthyl-derived amine thiourea organocatalyst has been developed and demonstrated to efficiently catalyze Michael addition reactions (using as low as 1 mol % loading) of diketones to nitroalkenes with remarkably hi