866959-17-3

Upstream product

• 866823-59-8 (2R,4S)-5-hexene-1,2,4-triol 
• 96852-88-9 3,5,6-trideoxy-1,2-O-isopropylidene-α-D-ribo-hex-5-enofuranoside 
• 637005-58-4 (2S,3R,5S)-5-Vinyl-tetrahydro-furan-2,3-diol 
• 117064-89-8 1-[2,2-dimethyl-(4R)-1,3-dioxolan-4-yl]-(2S)-3-buten-2-ol 
• 100-39-0 benzyl bromide 

Downstream Products

• 889881-73-6 (S)-3-Benzyloxy-4-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-butyraldehyde 
• 866823-64-5 ((2S,4R,6R)-4-Benzyloxy-6-methoxymethoxymethyl-tetrahydro-pyran-2-yl)-acetaldehyde 
• 866823-58-7 ethyl 5-benzyloxy-7,8-dihydroxy-(E,5R,7R)-2-octenoate 
• 866823-62-3 ((2S,4R,6R)-4-Benzyloxy-6-hydroxymethyl-tetrahydro-pyran-2-yl)-acetic acid ethyl ester 
• 866823-61-2 ethyl 5-benzyloxy-6-[2,2-dimethyl-(4R)-1,3-dioxolan-4-yl]-(E,5R)-2-hexenoate 
• 866823-57-6 ((2S,4R,6R)-4-Benzyloxy-6-methoxymethoxymethyl-tetrahydro-pyran-2-yl)-acetic acid ethyl ester 
• 866823-65-6 (R)-1-((2R,4R,6R)-4-Benzyloxy-6-methoxymethoxymethyl-tetrahydro-pyran-2-yl)-pent-4-en-2-ol 
• 866823-56-5 6-[4-benzyloxy-6-methoxymethoxymethyl-(2S,4R,6R)-2H,3H,4H,5H-2-pyranylmethyl]-(6R)-2H,5H-2-pyranone 
• 866823-67-8 4-benzyloxy-2-[2-ethoxy-(2S,6R)-2H,5H-6-pyranylmethyl]-6-methoxymethoxymethyl-(2R,4R,6R)-2H,3H,4H,5H-pyran 
• 866823-66-7 Acrylic acid (R)-1-((2S,4R,6R)-4-benzyloxy-6-methoxymethoxymethyl-tetrahydro-pyran-2-ylmethyl)-but-3-enyl ester 
• 866823-60-1 3-benzyloxy-4-[2,2-dimethyl-(4R)-1,3-dioxolan-4-yl]-(3R)-butan-1-ol 

Relevant academic research and scientific papers

General strategy towards chiral methylene bis-pyrans: Synthesis of the C2-C16 fragment of phorboxazole A

A chiral methylene bis-pyran fragment was synthesized by making efficient use of an oxy-anion intramolecular Michael addition, Brown's asymmetric allylation and Grubb's ring closing metathesis reactions in a stereoselective manner.