866994-24-3Relevant academic research and scientific papers
Synthesis of novel enantiopure fluorinated building blocks from acyclic chiral allylsilanes
Tredwell, Matthew,Tenza, Kenny,Pacheco, Ma. Carmen,Gouverneur, Veronique
, p. 4495 - 4497 (2005)
(Chemical Equation Presented) Homochiral β-fluorinated γ,δ-unsaturated carboxylic acids with an allylic fluorinated stereogenic center are available from the corresponding enantiopure allylsilanes. The key step for introduction of the fluorine substituent
Fluorination process
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Page/Page column 13, (2008/06/13)
Compounds of formula (II), (IIIa) or (IIIb) (variables are described in the specification) are prepared by fluorination of β,γ-unsaturated alkyl silanes. These compounds are useful as building blocks in the pharmaceutical industry.
