867006-59-5

Basic information

• Product Name: Benzonitrile, 5-bromo-2-(4-morpholinylmethyl)-
• CAS NO: 867006-59-5
• Molecular Formula: C12H13BrN2O
• Molecular Weight: 281.152
• Mol File: 867006-59-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 5-bromo-2-(4-morpholinylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 5-bromo-2-(4-morpholinylmethyl)-(867006-59-5)
• EPA Substance Registry System: Benzonitrile, 5-bromo-2-(4-morpholinylmethyl)-(867006-59-5)

Safety Data

• Hazardous Substances Data: 867006-59-5(Hazardous Substances Data)

Upstream product

• 156001-51-3 3-Bromo-6-methyl-benzonitrile 
• 110-91-8 morpholine 
• 523977-64-2 5-bromo-2-formylbenzonitrile 
• 156001-53-5 5-bromo-2-(bromomethyl)benzonitrile 

Downstream Products

• 1403256-12-1 3'-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4'-(morpholinomethyl)-[1,1'-biphenyl]-3-carboxamide 
• 867006-60-8 5-(6-benzyloxy-5-ethyl-2-methylpyridin-3-yl)-2-(morpholin-4-yl)methyl-benzonitrile 

Relevant articles and documents

TBK/IKK INHIBITOR COMPOUNDS AND USES THEREOF

The present invention relates to compounds of Formula I and pharmaceutically acceptable compositions thereof, useful as TBK/IKKε inhibitors.

SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP)

The present invention discloses and claims a series of 2,3,5-substituted pyridone derivatives as defined herein. This invention also relates to methods of making these compounds. The compounds of this invention are inhibitors of poly(adenosine 5'-diphosphate ribose) polymerase (PARP) and are therefore useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases, including diseases associated with the central nervous system and cardiovascular disorders.