867062-95-1 Usage
Description
Fmoc-N-amido-PEG3-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Chemical Properties
White powder
Uses
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic Acid has been used as a reactant for the preparation of vaccines.
Check Digit Verification of cas no
The CAS Registry Mumber 867062-95-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,7,0,6 and 2 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 867062-95:
(8*8)+(7*6)+(6*7)+(5*0)+(4*6)+(3*2)+(2*9)+(1*5)=201
201 % 10 = 1
So 867062-95-1 is a valid CAS Registry Number.
InChI:InChI=1/C24H29NO7/c25-22(16-31-14-13-30-12-11-29-10-9-23(26)27)24(28)32-15-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-8,21-22H,9-16,25H2,(H,26,27)
867062-95-1Relevant articles and documents
Polypeptide, protein PEG modifier synthesis method
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Paragraph 0019; 0020; 0026, (2017/09/26)
The present invention discloses a synthesis route and an operation method of a peptide and protein pegylation agent, wherein the pegylation agent is used for polypeptides and drug structure modification, the raw materials of the method are cheap, and the amount of the polyethylene glycol can be defined.
