Cas 867064-26-4,(9S)-9-{2-[(R-2-tert-butoxycarbonylamino-2-ethoxycarbonyl)ethanesulfanyl]ethoxycarbonyloxy}-9-ethyl-1-pentyl-1H,12H-pyrano[3'',4'':6',7']indolizino[1',2':6,5]pyrido[4,3,2-de]quinazoline-10,13(9H,15H)-dione

867064-26-4

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Product Name: (9S)-9-{2-[(R-2-tert-butoxycarbonylamino-2-ethoxycarbonyl)ethanesulfanyl]ethoxycarbonyloxy}-9-ethyl-1-pentyl-1H,12H-pyrano[3'',4'':6',7']indolizino[1',2':6,5]pyrido[4,3,2-de]quinazoline-10,13(9H,15H)-dione
Synonyms:
CAS NO:867064-26-4
Molecular Formula:
Molecular Weight: 777.896
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (9S)-9-{2-[(R-2-tert-butoxycarbonylamino-2-ethoxycarbonyl)ethanesulfanyl]ethoxycarbonyloxy}-9-ethyl-1-pentyl-1H,12H-pyrano[3'',4'':6',7']indolizino[1',2':6,5]pyrido[4,3,2-de]quinazoline-10,13(9H,15H)-dione(CAS DataBase Reference)
NIST Chemistry Reference: (9S)-9-{2-[(R-2-tert-butoxycarbonylamino-2-ethoxycarbonyl)ethanesulfanyl]ethoxycarbonyloxy}-9-ethyl-1-pentyl-1H,12H-pyrano[3'',4'':6',7']indolizino[1',2':6,5]pyrido[4,3,2-de]quinazoline-10,13(9H,15H)-dione(867064-26-4)
EPA Substance Registry System: (9S)-9-{2-[(R-2-tert-butoxycarbonylamino-2-ethoxycarbonyl)ethanesulfanyl]ethoxycarbonyloxy}-9-ethyl-1-pentyl-1H,12H-pyrano[3'',4'':6',7']indolizino[1',2':6,5]pyrido[4,3,2-de]quinazoline-10,13(9H,15H)-dione(867064-26-4)

Safety Data

Hazard Codes: N/A
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Safety Statements: N/A
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RTECS:
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PackingGroup: N/A
Hazardous Substances Data: 867064-26-4(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 867064-26-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,7,0,6 and 4 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 867064-26:
(8*8)+(7*6)+(6*7)+(5*0)+(4*6)+(3*4)+(2*2)+(1*6)=194
194 % 10 = 4
So 867064-26-4 is a valid CAS Registry Number.

867064-26-4Upstream product

867064-26-4Downstream Products

867064-26-4Relevant academic research and scientific papers

Synthesis and biological activities of a pH-dependently activated water-soluble prodrug of a novel hexacyclic camptothecin analog

Ohwada, Jun,Ozawa, Sawako,Kohchi, Masami,Fukuda, Hiroshi,Murasaki, Chikako,Suda, Hitomi,Murata, Takeshi,Niizuma, Satoshi,Tsukazaki, Masao,Ori, Kazutomo,Yoshinari, Kiyoshi,Itezono, Yoshiko,Endo, Mika,Ura, Masako,Tanimura, Hiromi,Miyazaki, Yoko,Kawashima, Akira,Nagao, Shunsuke,Namba, Eitarou,Ogawa, Koutarou,Kobayashi, Kazuko,Okabe, Hisafumi,Umeda, Isao,Shimma, Nobuo

scheme or table, p. 2772 - 2776 (2009/12/31)

CH0793076 (1) is a novel hexacyclic camptothecin analog showing potent antitumor activity in various human caner xenograft models. To improve the water solubility of 1, water-soluble prodrugs were designed to generate an active drug 1 nonenzymatically, th

AGENT FOR PREVENTING OR TREATING PANCREAS CANCER, OVARY CANCER OR LIVER CANCER CONTAINING NOVEL WATER-SOLUBLE PRODRUG

-

, (2008/12/06)

Preventive or therapeutic agents for pancreatic cancer, ovarian cancer, or liver cancer of the present invention comprise a water-soluble prodrug represented by formula 1 described below, or a pharmaceutically acceptable salt, or a hydrate or solvate of t

NOVEL ANTICANCER CONCOMITANT DRUG

-

Page/Page column 46-47, (2008/12/05)

A cancer therapeutic agent according to the present invention comprises a combination of compound A described below, or a pharmaceutically acceptable salt thereof, and compound B described below, or a pharmaceutically acceptable salt thereof: Compound A:

NOVEL WATER-SOLUBLE PRODRUG

-

Page/Page column 48-49, (2010/11/25)

An objective of the present invention is to provide water-soluble prodrugs that can be administered parenterally, and which show excellent water solubility and small interspecies or individual differences and are rapidly converted to the active form by ch

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