867065-85-8 Usage
Description
TERT-BUTYL TETRAHYDROPYRIMIDINE-1(2H)-CARBOXYLATE is a chemical compound that serves as an intermediate in the synthesis of HAT inhibitors. It is a versatile building block in organic chemistry, particularly in the development of pharmaceuticals and agrochemicals.
Uses
Used in Pharmaceutical Industry:
TERT-BUTYL TETRAHYDROPYRIMIDINE-1(2H)-CARBOXYLATE is used as a key intermediate in the synthesis of HAT inhibitors for the development of potential therapeutic agents. These inhibitors target histone acetyltransferases (HATs), enzymes that play a crucial role in the regulation of gene expression and are implicated in various diseases, including cancer and neurodegenerative disorders.
Used in Agrochemical Industry:
TERT-BUTYL TETRAHYDROPYRIMIDINE-1(2H)-CARBOXYLATE is also utilized as a precursor in the production of agrochemicals, specifically in the development of novel pesticides and herbicides. Its unique chemical properties allow for the creation of compounds with improved efficacy and selectivity, contributing to more sustainable agricultural practices.
Check Digit Verification of cas no
The CAS Registry Mumber 867065-85-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,7,0,6 and 5 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 867065-85:
(8*8)+(7*6)+(6*7)+(5*0)+(4*6)+(3*5)+(2*8)+(1*5)=208
208 % 10 = 8
So 867065-85-8 is a valid CAS Registry Number.
867065-85-8Relevant articles and documents
Amidines analogs thereof to catalyze the nitrogen mixed fat surrounds uncle-butoxy carbonyl list protection method (by machine translation)
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Paragraph 0034, (2019/10/02)
The present invention is a method under the catalysis of the analogs of the amidines, to two nitrogen heterolipid animal fat link Boc protection of single green synthesis method. It is characterized in that the various two nitrogen heterolipid animal fat link compound water and alcohol as the solvent, in the presence of a certain amount of acid, joins the trunk and its analogs catalyst, di-T-butyl ester for (Boc anhydride) as Boc protecting reagent, the temperature of the reaction is carried out, the final by reduced pressure distillation to obtain the target product is separated from the single N - Boc - two nitrogen heterolipid [...] compound. The invention innovative use of the amidines its analogues as single Boc protecting catalyst, more traditional synthetic method more green environmental protection, safety, and cost saving. (by machine translation)
Inhibitors of histone deacetylase
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Page/Page column 34, (2010/02/14)
Disclosed are compounds which inhibit histone deacetylase (HDAC) enzymatic activity. Also disclosed are pharmaceutical compositions comprising such compounds as well as methods to treat conditions, particularly proliferative conditions, mediated at least in part by HDAC.
