867214-04-8

Basic information

• Product Name: 5-{{4-[1-Benzyloxy-meth-(Z)-ylidene]-hexanoyl}-[2-(6-methoxy-1-methyl-1H-indol-3-yl)-ethyl]-amino}-[1,3,4]oxadiazole-2-carboxylic acid methyl ester
• Synonyms: 5-{{4-[1-Benzyloxy-meth-(Z)-ylidene]-hexanoyl}-[2-(6-methoxy-1-methyl-1H-indol-3-yl)-ethyl]-amino}-[1,3,4]oxadiazole-2-carboxylic acid methyl ester
• CAS NO: 867214-04-8
• Molecular Weight: 546.623
• Mol File: 867214-04-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-{{4-[1-Benzyloxy-meth-(Z)-ylidene]-hexanoyl}-[2-(6-methoxy-1-methyl-1H-indol-3-yl)-ethyl]-amino}-[1,3,4]oxadiazole-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-{{4-[1-Benzyloxy-meth-(Z)-ylidene]-hexanoyl}-[2-(6-methoxy-1-methyl-1H-indol-3-yl)-ethyl]-amino}-[1,3,4]oxadiazole-2-carboxylic acid methyl ester(867214-04-8)
• EPA Substance Registry System: 5-{{4-[1-Benzyloxy-meth-(Z)-ylidene]-hexanoyl}-[2-(6-methoxy-1-methyl-1H-indol-3-yl)-ethyl]-amino}-[1,3,4]oxadiazole-2-carboxylic acid methyl ester(867214-04-8)

Safety Data

• Hazardous Substances Data: 867214-04-8(Hazardous Substances Data)

Upstream product

• 64954-92-3 N¹-methyl-6-methoxytryptamine 
• 2955-62-6 methyl 4-oxohexanoate 
• 1117-74-4 4-oxohexanoic acid 
• 867214-10-6 C₁₃H₁₈N₄O₂ 
• 867214-12-8 imidazole-1-carboxylic acid [2-(6-methoxy-1-methyl-1H-indol-3-yl)-ethyl]-amide 
• 473742-43-7 methyl (Z)-5-benzyloxy-4-ethylpent-4-enoate 
• 202807-44-1 6-methoxy-1-methyl-1H-indole-3-carbaldehyde 
• 473742-41-5 (Z)-5-(benzyloxy)-4-ethylpent-4-enoic acid 
• 867214-15-1 5-[2-(6-methoxy-1-methyl-1H-indol-3-yl)-ethylamino]-[1,3,4]oxadiazole-2-carboxylic acid methyl ester 
• 1968-17-8 6-methoxy-1-methyl-1H-indole 
• 867214-13-9 C₁₆H₂₀N₄O₅ 

Downstream Products

• 2182-14-1 vindoline 
• 910558-58-6 C₃₉H₅₄N₂O₆SSi 
• 910559-45-4 C₃₉H₅₄N₂O₆SSi 
• 910558-57-5 C₃₉H₅₄N₂O₇Si 
• 867214-45-7 C₃₉H₅₄N₂O₇Si 
• 910558-55-3 C₃₀H₃₄N₂O₆ 
• 910559-34-1 C₃₀H₃₄N₂O₆ 

Relevant articles and documents

Total synthesis of (-)- and ent-(+)-vindoline

(Chemical Equation Presented) Two exceptionally concise total syntheses of (-)- and ent-(+)-vindoline are detailed enlisting a diastereoselective tandem [4 + 2]/[3 + 2] cycloaddition of a 1,3,4-oxadiazole. The unique reaction cascade assembles the fully functionalized pentacyclic ring system of vindoline in a single step that forms four C-C bonds and three rings while introducing all requisite functionality and setting all six stereocenters within the central ring including three contiguous and four total quaternary centers.