86732-28-7

Basic information

• Product Name: 2-Methyl-octahydro-pyrrolo[3,4-c]pyrrole
• Synonyms: 2-Methyl-octahydro-pyrrolo[3,4-c]pyrrole;cis-2-Methylhexahydropyrrolo[3,4-c]pyrrole;octahydropyrrolo[3,4-c]pyrrole;(3aR*,6aS*)-2-methyloctahydropyrrolo[3,4-c]pyrrole(SALTDATA: 2HCl);2-Methylhexahydropyrrolo[3,4-c]pyrrole;5-Methyloctahydropyrrolo[3,4-c]pyrrole;Pyrrolo[3,4-c]pyrrole, octahydro-2-Methyl-;rac-(3aR,6aS)-2-Methyloctahydropyrrolo[3,4-c]pyrrole dihydrochloride (SALTDATA: 2HCl)
• CAS NO: 86732-28-7
• Molecular Formula: C₇H₁₄N₂
• Molecular Weight: 126.2
• Product Categories: Amines and Anilines;Heterocycles;pharmacetical;API intermediates
• Mol File: 86732-28-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 182℃
• Flash Point: 73℃
• Appearance: /
• Density: 0.970
• Vapor Pressure: 0.85mmHg at 25°C
• Refractive Index: 1.486
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 10.90±0.20(Predicted)
• CAS DataBase Reference: 2-Methyl-octahydro-pyrrolo[3,4-c]pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-octahydro-pyrrolo[3,4-c]pyrrole(86732-28-7)
• EPA Substance Registry System: 2-Methyl-octahydro-pyrrolo[3,4-c]pyrrole(86732-28-7)

Safety Data

• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39
• Hazardous Substances Data: 86732-28-7(Hazardous Substances Data)

Usage

Uses

2-Methyloctahydropyrrolo[3,4-c]pyrrole is used as a reagent in the synthesis of novel aryl substituted urea derivatives which can exhibit antimicrobial activity against pathogenic bacteria and fungi. 2-Methyloctahydropyrrolo[3,4-c]pyrrole is also used in the preparation of 3-hydroxyquinazoline-2,4-dione antibacterial agents.

InChI:InChI=1/C7H14N2/c1-9-4-6-2-8-3-7(6)5-9/h6-8H,2-5H2,1H3

Upstream product

• 86732-18-5 2-benzyl-5-methyl-octahydro-pyrrolo[3,4-c]pyrrole 
• 86732-01-6 4-Benzylcarbamoyl-1-methyl-1H-pyrrole-3-carboxylic acid 
• 86732-11-8 1-benzyl-N-methyl-1H-pyrrole-3,4-dicarboximide 
• 86731-93-3 1-methyl-1H-pyrrole-3,4-dicarboxylic anhydride 
• 86731-91-1 1-methyl-pyrrole-3,4-dicarboxylic acid 
• 86755-80-8 cis-hexahydro-2-methyl-5benzylpyrrolo<3,4-c>pyrrole 

Downstream Products

• 1429176-55-5 (4S)-4-isopropyl-3-(2-((⁽¹⁾-1-(4-((5-methylhexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)methyl)phenyl)ethyl)amino)pyrimidin-4-yl)oxazolidin-2-one 
• 861119-08-6 2-(5-methylhexahydropyrrolo[3,4-c]pyrrol-2-yl)xanthen-9-one 

Relevant articles and documents

Amino-substituted tricyclic derivatives and methods of use

Compounds of formula (I) wherein A and B are amine-substituted sidechains, Y1 and Y2 form various tricyclic cores, Xa and Xb are C, CH, or N, as defined herein, and Rx is an optional substituent. Compounds and compositions of formula (I) are contemplated as well as methods for treating conditions or disorders prevented by or ameliorated by α7nAChR ligands that encompass compounds of formula (I) and other tricyclic derivatives. Methods of using amino-substituted tricyclic derivatives also are described herein.

8-vinyl- and 9-ethinyl-quinolone-carboxylic acids

The invention relates to new 8-vinyl- and 8-ethinylquinolonecarboxylic acids, process for their preparation, and antibacterial agents and feed additives containing them.

Synthesis and Carbon-13 NMR Study of 2-Benzyl, 2-Methyl, 2-Aryloctahydropyrrolopyrroles and the 1,2,3,5-Tetrahydropyrrolopyrrole Ring System

2-Benzyl, 2-phenyl, 2-(3-methoxyphenyl) and 2-(3-trifluoromethylphenyl)octahydropyrrolopyrrole (9a, 9b, 9c and 9d, respectively) were prepared in five steps from 1-benzylpyrrole-3,4-dicarboxylic acid (2). 2-Methyloctahydropyrrolopyrrole (9'a