867330-99-2

Basic information

• Product Name: 1,2,4-Benzotriazin-3-amine, 7-(2,6-dimethylphenyl)-5-nitro-, 1-oxide
• CAS NO: 867330-99-2
• Molecular Formula: C15H13N5O3
• Molecular Weight: 311.3
• Mol File: 867330-99-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,2,4-Benzotriazin-3-amine, 7-(2,6-dimethylphenyl)-5-nitro-, 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,4-Benzotriazin-3-amine, 7-(2,6-dimethylphenyl)-5-nitro-, 1-oxide(867330-99-2)
• EPA Substance Registry System: 1,2,4-Benzotriazin-3-amine, 7-(2,6-dimethylphenyl)-5-nitro-, 1-oxide(867330-99-2)

Safety Data

• Hazardous Substances Data: 867330-99-2(Hazardous Substances Data)

Upstream product

• 875-51-4 4-Bromo-2-nitroaniline 
• 6298-38-0 7-bromo-1-oxido-1,2,4-benzotriazin-1-ium-3-amine 
• 119707-95-8 2-nitro-4-bromophenylguanidine 
• 867330-98-1 7-bromo-5-nitro-1-oxy-benzo[1,2,4]triazin-3-ylamine 
• 100379-00-8 2,6-dimethylbenzene boronic acid 

Downstream Products

• 867331-00-8 4-[7-(2,6-dimethyl-phenyl)-5-nitro-1-oxy-benzo[1,2,4]triazin-3-ylamino]-N-(2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide 
• 867331-59-7 7-(2,6-dimethyl-phenyl)-N₃-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-benzo[1,2,4]triazine-3,5-diamine 
• 867331-58-6 [7-(2,6-dimethyl-phenyl)-5-nitro-1-oxy-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine 

Relevant articles and documents

Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine-a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays

We describe the identification of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine (3), a potent, orally active Src inhibitor with desirable PK properties, demonstrated activity in human tumor cell lines