867331-59-7

Basic information

• Product Name: 7-(2,6-dimethyl-phenyl)-N₃-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-benzo[1,2,4]triazine-3,5-diamine
• Synonyms: 7-(2,6-dimethyl-phenyl)-N₃-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-benzo[1,2,4]triazine-3,5-diamine
• CAS NO: 867331-59-7
• Molecular Weight: 454.575
• Mol File: 867331-59-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-(2,6-dimethyl-phenyl)-N₃-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-benzo[1,2,4]triazine-3,5-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(2,6-dimethyl-phenyl)-N₃-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-benzo[1,2,4]triazine-3,5-diamine(867331-59-7)
• EPA Substance Registry System: 7-(2,6-dimethyl-phenyl)-N₃-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-benzo[1,2,4]triazine-3,5-diamine(867331-59-7)

Safety Data

• Hazardous Substances Data: 867331-59-7(Hazardous Substances Data)

Upstream product

• 867331-58-6 [7-(2,6-dimethyl-phenyl)-5-nitro-1-oxy-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine 
• 875-51-4 4-Bromo-2-nitroaniline 
• 6298-38-0 7-bromo-1-oxido-1,2,4-benzotriazin-1-ium-3-amine 
• 867330-99-2 7-(2,6-dimethyl-phenyl)-5-nitro-1-oxy-benzo[1,2,4]triazin-3-ylamine 
• 867330-98-1 7-bromo-5-nitro-1-oxy-benzo[1,2,4]triazin-3-ylamine 
• 119707-95-8 2-nitro-4-bromophenylguanidine 

Relevant articles and documents

Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine-a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays

We describe the identification of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine (3), a potent, orally active Src inhibitor with desirable PK properties, demonstrated activity in human tumor cell lines