867333-04-8

Basic information

• Product Name: 6-Chloro-2-fluoro-3-methoxyphenylboronicacid
• Synonyms: 6-Chloro-2-fluoro-3-methoxyphenylboronicacid;2-Fluoro-3-methoxy-6-chlorophenylboronic acid;(6-Chloro-2-fluoro-3-methoxyphenyl);B-(6-chloro-2-fluoro-3-methoxy-phenyl)boronic acid
• CAS NO: 867333-04-8
• Molecular Formula: C₇H₇BClFO₃
• Molecular Weight: 204.39
• Product Categories: Aryl;Organoborons
• Mol File: 867333-04-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 355.694°C at 760 mmHg
• Flash Point: 168.918°C
• Appearance: /
• Density: 1.405g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.525
• PKA: 7.60±0.58(Predicted)
• CAS DataBase Reference: 6-Chloro-2-fluoro-3-methoxyphenylboronicacid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Chloro-2-fluoro-3-methoxyphenylboronicacid(867333-04-8)
• EPA Substance Registry System: 6-Chloro-2-fluoro-3-methoxyphenylboronicacid(867333-04-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 867333-04-8(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 867333-04-8 differently. You can refer to the following data:
1. suzuki reaction
2. 6-Chloro-2-fluoro-3-methoxyphenylboronic acid

InChI:InChI=1/C7H7BClFO3/c1-13-5-3-2-4(9)6(7(5)10)8(11)12/h2-3,11-12H,1H3

Upstream product

• 121-43-7 Trimethyl borate 
• 452-09-5 4-chloro-2-fluoro-1-methoxybenzene 

Relevant articles and documents

Design and application of a low-temperature continuous flow chemistry platform

A flow reactor platform technology applicable to a broad range of low temperature chemistry is reported. The newly developed system captures the essence of running low temperature reactions in batch and represents this as a series of five flow coils, each with independently variable volume. The system was initially applied to the functionalization of alkynes, Grignard addition reactions, heterocycle functionalization, and heteroatom acetylation. This new platform has then been used in the preparation of a 20-compound library of polysubstituted, fluorine-containing aromatic substrates from a sequential metalation-quench procedure and can be readily adapted to provide gaseous electrophile inputs such as carbon dioxide using a tube-in-tube reactor.