867339-45-5Relevant academic research and scientific papers
Structure based design of simplified analogues of insect kinins
Kamoune, Laila,De Borggraeve, Wim M.,Verbist, Bie M. P.,Broeck, Jozef Vanden,Coast, Geoffrey M.,Compernolle, Frans,Hoornaert, Georges
, p. 9555 - 9562 (2005)
Based on a receptor interaction model, simplified analogues of insect kinins were prepared. The compounds were templated on a conformationally restricted amino piperidinone carboxylate scaffold. The conformation of the analogues was studied by NMR and the
A novel and versatile entry to asymmetrically substituted pyrazines
Mehta, Vaibhav Pravinchandra,Sharma, Anuj,Van Hecke, Kristof,Van Meervelt, Luc,Van Der Eycken, Erik
, p. 2382 - 2388 (2008/09/19)
(Chemical Equation Presented) A novel and convenient procedure for the synthesis of asymmetrically tri- and tetrasubstituted pyrazines starting from para-methoxybenzyl-protected 3,5-dichloro-2(1H)-pyrazinones was elaborated. The key step is the conversion
