393860-82-7

Basic information

• Product Name: 2(1H)-Pyrazinone, 3,5-dichloro-1-[(4-methoxyphenyl)methyl]-
• CAS NO: 393860-82-7
• Molecular Formula: C12H10Cl2N2O2
• Molecular Weight: 285.13
• Mol File: 393860-82-7.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 2(1H)-Pyrazinone, 3,5-dichloro-1-[(4-methoxyphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Pyrazinone, 3,5-dichloro-1-[(4-methoxyphenyl)methyl]-(393860-82-7)
• EPA Substance Registry System: 2(1H)-Pyrazinone, 3,5-dichloro-1-[(4-methoxyphenyl)methyl]-(393860-82-7)

Safety Data

• Hazardous Substances Data: 393860-82-7(Hazardous Substances Data)

Usage

Classification

Macrolide antibiotic

Function

Stops the growth of bacteria

Effective against

A wide range of bacteria, including both gram-positive and gram-negative bacteria

Common uses

Respiratory tract infections, skin and soft tissue infections, and certain sexually transmitted infections

Available forms

Tablets, capsules, and oral suspension

Dosage frequency

One to two times a day, depending on the specific infection being treated

Importance

Follow dosage and frequency instructions provided by a healthcare professional when taking this medication.

Upstream product

• 79-37-8 oxalyl dichloride 
• 2393-23-9 4-methoxy-benzylamine 
• 63086-28-2 2-((4-methoxybenzyl)amino)acetonitrile 

Downstream Products

• 817575-50-1 3-benzyl-5-chloro-1-(4-methoxybenzyl)-2(1H)-pyrazinone 
• 934542-63-9 5-[3-(ethylsulfonyl)phenyl]-7-(4-methoxybenzyl)-3-methyl-7,9-dihydro-dipyrido[2,3-b;4',3'-d]pyrrol-8-one 
• 934542-60-6 5-chloro-1-(4-methoxybenzyl)-3-(5-methyl-3-((trimethylsilyl)ethynyl)pyridin-2-ylamino)pyrazin-2(1H)-one 
• 934542-61-7 7-(4-methoxybenzyl)-3-methyl-5-trimethylsilanyl-7,9-dihydro-dipyrido[2,3-b;4',3'-d]pyrrol-8-one 
• 934542-62-8 5-iodo-7-(4-methoxybenzyl)-3-methyl-7,9-dihydro-dipyrido[2,3-b;4',3'-d]pyrrol-8-one 
• 1451178-93-0 5-chloro-7-(4-methoxybenzyl)-8-oxo-7,8-dihydroimidazo[1,2-a]-pyrazine-3-carbaldehyde 
• 1415565-66-0 5-chloro-1-(4-methoxybenzyl)-3-(prop-2-ynylamino)pyrazin-2(1H)-one 
• 1415565-78-4 7-(4-methoxybenzyl)-3-methyl-5-(thiophen-3-yl)imidazo[1,2-a]pyrazin-8(7H)-one 
• 1415565-83-1 (Z)-5-chloro-3-((2-chloropyridin-4-yl)methylene)-7-(4-methoxybenzyl)-2,3-dihydroimidazo[1,2-a]pyrazin-8(7H)-one 
• 1415565-88-6 5-chloro-3-(3-(2-chloropyridin-4-yl)prop-2-ynylamino)-1-(4-methoxybenzyl)pyrazin-2(1H)-one 
• 1415565-56-8 5-chloro-7-(4-methoxybenzyl)-3-methylimidazo[1,2-a]pyrazin-8(7H)-one 
• 1394231-06-1 diethyl 2-(6-chloro-4-(4-methoxybenzyl)-3-oxo-3,4-dihydropyrazin-2-yl)malonate 
• 1394231-19-6 ethyl 2-(6-chloro-4-(4-methoxybenzyl)-3-oxo-3,4-dihydropyrazin-2-yl)acetate 
• 1382136-28-8 4-[6-chloro-4-(4-methoxy-benzyl)-3-oxo-3,4-dihydro-pyrazin-2-ylethynyl]-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

NOVEL 4-(ARYL)-N-(3-ALKOXYFURO[2,3-B]PYRAZIN-2-YL)-PIPERAZINE-1-CARBOXAMIDE DERIVATIVE AND ANTIPROLIFERATIVE EFFECT THEREOF

The present invention relates to a novel 4-(aryl)-N-(3-alkoxyfuro[3,2-b]pyrazin-2-yl)-piperazine-1-carboxamide derivative compound useful in the prevention or treatment of cancer; a preparation method thereof; and a pharmaceutical composition comprising t

AKT / PKB INHIBITORS

The invention relates to a series of compounds with particular activity as inhibitors of the serine-threonine kinase AKT. Also provided are pharmaceutical compositions comprising same as well as methods for treating cancer.

Diversity-oriented synthesis of substituted furo[2,3-b]pyrazines

A highly efficient method for the synthesis of diversely substituted furo[2,3-b]pyrazines has been elaborated. The Ag+- or iodine-mediated electrophilic cyclization of readily generated 5-chloro-3-substituted ethynyl-1-(4-methoxybenzyl)-pyrazin-2(1H)-ones affords substituted furo[2,3-b]pyrazines, which undergo various palladium catalyzed reactions to generate a library of difficult to attain diversely substituted furo[2,3-b]pyrazines. CSIRO 2009.