867350-27-4Relevant articles and documents
[Cp*RhIII] in an Ionic Liquid as a Highly Efficient and Recyclable Catalytic Medium for Regio- and Diastereoselective Csp3–H Carbenoid Insertion
Li, Jianglian,Zhou, Lin,Wang, Yaoling,Ma, Qiang,Lei, Yuan,Lai, Ruizhi,Luo, Yi,Hai, Li,Wu, Yong
, p. 7448 - 7451 (2019)
Reported herein is a bidentate-assisted Csp3–H bond insertion using Cp*RhIII/IL as a highly efficient and recyclable catalytic medium, while showing good functional group tolerance. Notably, the application of ionic liquid not only lowered the temperature, but also enhanced the diastereoselectivity of this reaction. This work significantly expanded the scope of ionic liquids in Csp3–H functionalizations.
Cobalt-Catalyzed Selective Synthesis of Isoquinolines Using Picolinamide as a Traceless Directing Group
Kuai, Changsheng,Wang, Lianhui,Li, Bobin,Yang, Zhenhui,Cui, Xiuling
supporting information, p. 2102 - 2105 (2017/04/27)
Picolinamide has first been employed as a traceless directing group for the cobalt-catalyzed oxidative annulation of benzylamides with alkynes to synthesize isoquinolines through C-H/N-H bonds activation. Oxygen is used as a terminal oxidant. This protocol exhibits good functional group tolerance and excellent regioselectivity. Both terminal and internal alkynes can be efficiently applied to this catalytic system as substrates.
Palladium-catalyzed alkenylation and alkynylation of ortho-C(sp 2)-H bonds of benzylamine picolinamides
Zhao, Yingsheng,He, Gang,Nack, William A.,Chen, Gong
supporting information; experimental part, p. 2948 - 2951 (2012/08/07)
An efficient functionalization of ortho-C(sp2)-H bonds of picolinamide (PA)-protected benzylamine substrates with a range of vinyl iodides as well as acetylenic bromide is reported. ortho-Phenyl benzoic acid (oPBA) acts as an effective promoter in this reaction system. This method provides a practical strategy to access highly functionalized benzylamine compounds for organic synthesis.
