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Benzaldehyde, 4-[2-(methylthio)-6-phenylpyrido[2,3-d]pyrimidin-7-yl]- is a complex organic compound with the molecular formula C21H16N4OS. It is a derivative of benzaldehyde, featuring a pyrido[2,3-d]pyrimidine core structure, which is a fused ring system consisting of a pyridine and a pyrimidine. The compound is characterized by a methylthio group (-SCH3) at position 2 and a phenyl group at position 6 of the pyrido[2,3-d]pyrimidine ring. This chemical structure endows the compound with potential applications in pharmaceuticals and materials science, particularly as a building block for the synthesis of more complex molecules with specific biological activities.

867353-44-4

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867353-44-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 867353-44-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,7,3,5 and 3 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 867353-44:
(8*8)+(7*6)+(6*7)+(5*3)+(4*5)+(3*3)+(2*4)+(1*4)=204
204 % 10 = 4
So 867353-44-4 is a valid CAS Registry Number.

867353-44-4Relevant academic research and scientific papers

Development of Pyridopyrimidines as Potent Akt1/2 Inhibitors

Wu, Zhicai,Hartnett, John C.,Neilson, Lou Anne,Robinson, Ronald G.,Fu, Sheng,Barnett, Stanley F.,Defeo-Jones, Deborah,Jones, Raymond E.,Kral, Astrid M.,Huber, Hans E.,Hartman, George D.,Bilodeau, Mark T.

, p. 1274 - 1279 (2008/09/19)

This communication reports a new synthetic route of pyridopyrimidines to facilitate their structural optimization in a library fashion and describes the development of pyridopyrimidines that have excellent enzymatic and cell potency against Akt1 and Akt2.

INHIBITORS OF AKT ACTIVITY

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Page/Page column 51, (2008/06/13)

The present invention is directed to compounds which contain substituted 5-deazapteridine moieties which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.

INHIBITORS OF AKT ACTIVITY

-

Page/Page column 48-49, (2010/02/14)

The present invention is directed to compounds which contain substituted napthyridines which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.

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