867367-80-4

Upstream product

• 303044-42-0 (2R,3R)-2-{(2R)-2-{[(1,1-dimethylethyl)diphenylsilyl]oxy}propyl}-3-ethenyloxirane 
• 55018-89-8 2,4-dimethoxy-6-methylbenzoyl chloride 
• 303044-38-4 (+)-(3R,4R,6R)-6-(hydroxy)-3,4-(oxiranyl)-hept-1-ene 
• 3686-57-5 2,4-dimethoxy-6-methylbenzoic acid 
• 64584-92-5 (R)-pent-4-en-2-ol 

Downstream Products

• 867367-82-6 (Z)-(4R,6R,8R)-17,19-Dimethoxy-4-methyl-12-phenylsulfanyl-3,7-dioxa-tricyclo[13.4.0.0^6,8]nonadeca-1⁽¹⁵⁾,9,16,18-tetraene-2,13-dione 
• 867367-81-5 2,4-Dimethoxy-6-(2-oxo-3-phenylsulfanyl-hex-5-enyl)-benzoic acid (R)-1-methyl-2-((2R,3R)-3-vinyl-oxiranyl)-ethyl ester 

Relevant academic research and scientific papers

Solution- and solid-phase synthesis of radicicol (monorden) and pochonin C

A modular synthesis for pochonin C and radicicol is reported. The two natural products were prepared in seven and eight steps, respectively, from three readily available fragments. Alternative syntheses of these compounds were achieved using a combination of polymer-bound reagents and solid phase reactions. The conformation of the two natural products was studied and compared by using 2D NMR spectroscopy.