86788-11-6

Basic information

• Product Name: 2-(N-acetyl-N-methylamino)phenyl 3-methyl-2-oxo-1-phenylbutyl sulfide
• Synonyms: 2-(N-acetyl-N-methylamino)phenyl 3-methyl-2-oxo-1-phenylbutyl sulfide
• CAS NO: 86788-11-6
• Molecular Weight: 341.474
• Mol File: 86788-11-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(N-acetyl-N-methylamino)phenyl 3-methyl-2-oxo-1-phenylbutyl sulfide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(N-acetyl-N-methylamino)phenyl 3-methyl-2-oxo-1-phenylbutyl sulfide(86788-11-6)
• EPA Substance Registry System: 2-(N-acetyl-N-methylamino)phenyl 3-methyl-2-oxo-1-phenylbutyl sulfide(86788-11-6)

Safety Data

• Hazardous Substances Data: 86788-11-6(Hazardous Substances Data)

Upstream product

• 21749-63-3 2-(methylamino)benzenethiol 
• 109334-46-5 N-methyl-2-S-benzylthioaniline 
• 82187-05-1 N-(2-Benzylsulfanyl-phenyl)-N-methyl-isobutyramide 
• 100-39-0 benzyl bromide 
• 108-24-7 acetic anhydride 
• 82187-14-2 3-Methyl-1-(2-methylamino-phenylsulfanyl)-1-phenyl-butan-2-one 

Downstream Products

• 705-58-8 3-methyl-1-phenyl-2-butanol 
• 2893-05-2 3-methyl-1-phenylbutan-2-one 
• 7332-95-8 3-methyl-1-phenylbutane-1,2-dione 
• 76650-13-0 1,1-dimethoxy-3-methyl-1-phenyl-2-butanone 
• 37112-24-6 1-chloro-3-methyl-1-phenyl-2-butanone 

Relevant articles and documents

Medium-ring Ketone Synthesis. Intramolecular Acylation of Sulfur-stabilized Carbanions: A Model Study

Intramolecular acylation of the sulfur-stabilized carbanions of the acyclic ester 9 and amide sulfides 11 was carried out as a model study for developing an effective method for the construction of medium-ring ketones by ring closure.Reaction of 9a-c or 11a-g with lithium diisopropylamide (LDA) proceeded smoothly and the expected keto sulfides 10a-c or 12a-g, respectively, were obtained.In the cases where R1 and/or R2 in 11 were normal alkyl groups, the reaction did not take place.However, these difficulties were readily overcome either by introducing a methyl group next to the carbonyl group or by converting the sulfides into the corresponding sulfoxides or sulfones.Acylation in the allyl sulfides 11b, d, f and the allyl sulfone 20b takes place at the α-position to the sulfur atom, yielding β,γ-unsaturated ketones.A reductive removal of the sulfide moiety or its conversion into other functional groups was also examined.