86805-13-2Relevant academic research and scientific papers
RING TRANSFORMATIONS OF SOME 4-AMINOPTERIDINE 3-OXIDES AND DERIVATIVES
Kocevar, Marjan,Stanovnik, Branko,Tisler, Miha
, p. 823 - 829 (2007/10/02)
Syntheses of 4-aminopteridine 3-oxides are described.The pyrimidine part undergoes transformations with various reagents to give 4-hydroxyaminopteridines, substituted pyrazines, or substituted 1,2,4-oxadiazolylpyrazines. s-Triazolo(1,5-a)pyrazines can be prepared from 1,2,4-oxadiazolylpyrazines.The ring opening of the pyrimidine part of pteridines proceeds either py a C2-N3 or N3-C4 bond cleavage.
