868083-06-1Relevant academic research and scientific papers
Design, synthesis, and biological evaluation of 4-alkyliden-beta lactams: New products with promising antibiotic activity against resistant bacteria
Broccolo, Francesco,Cainelli, Gianfranco,Caltabiano, Gianluigi,Cocuzza, Clementina E. A.,Fortuna, Cosimo G.,Galletti, Paola,Giacomini, Daria,Musumarra, Giuseppe,Musumeci, Rosario,Quintavalla, Arianna
, p. 2804 - 2811 (2007/10/03)
The design, synthesis, and antibacterial activity of 4-alkyliden-azetidin- 2-ones as new antimicrobial agents against multidrug-resistant pathogens is reported. 4-Alkyliden-azetidin-2-ones were easily obtained using an original protocol starting from 4-ac
4-Alkyliden-β-lactams conjugated to polyphenols: Synthesis and inhibitory activity
Cainelli, Gianfranco,Galletti, Paola,Garbisa, Spiridione,Giacomini, Daria,Sartor, Luigi,Quintavalla, Arianna
, p. 6120 - 6132 (2007/10/03)
A series of compounds combining the β-lactam and polyphenol scaffold have been prepared and evaluated for inhibition of human leukocyte elastase and matrix metallo-proteases MMP-2 and MMP-9. The design of these compounds has been based on the 'overlapping
