868132-33-6Relevant articles and documents
Access to macrocyclic endocyclic and exocyclic allylic alcohols by nickel-catalyzed reductive cyclization of ynals
Knapp-Reed, Beth,Mahandru, Gireesh M.,Montgomery, John
, p. 13156 - 13157 (2007/10/03)
Ni-catalyzed reductive macrocyclizations of ynals are reported. Disubstituted alkynes afford either endocyclic or exocyclic allylic alcohols depending on the ligand. Phosphine ligands favor the formation of endocyclic olefins, whereas N-heterocyclic carbe