868258-27-9Relevant academic research and scientific papers
Total synthesis of (+)-lithospermic acid by asymmetric intramolecular alkylation via catalytic C-H bond activation
O'Malley, Steven J.,Tan, Kian L.,Watzke, Anja,Bergman, Robert G.,Ellman, Jonathan A.
, p. 13496 - 13497 (2007/10/03)
The total synthesis of (+)-lithospermic acid is described. The efficient synthesis features an asymmetric alkylation via C-H bond activation to assemble the dihydrobenzofuran core of the natural product. This was accomplished via a chiral imine-directed C
