86839-78-3Relevant articles and documents
Syntheses and Reactions of Pyridazine Derivatives, XVIII: Synthesis of Novel Halogen Containing 5-Aroylpyridazine-4-carboxylic Acids and Phenyl 4-Pyridazinyl Ketones
Heinisch, Gottfried,Kirchner, Ingrid,Kurzmann, Ingeborg,Loetsch, Gerhard,Waglechner, Richard
, p. 508 - 515 (2007/10/02)
The ketocarboxylic acids 4c-h were prepared by Minisci-reaction of ethyl pyridazine-4-carboxylate, followed by alkaline hydrolysis of the resulting esters 2.Compounds 4 are also obtained by homolytic aroylation of pyridazine-4-carboxylic acid.The hitherto unknown aryl 4-pyridazinyl ketones 5c, d, f, g, h were prepared by decarboxylation of carboxylic acids 4.