868594-43-8 Usage
Uses
Used in Pharmaceutical Synthesis:
Benzyl-PEG7-amino serves as a key precursor in the synthesis of various pharmaceuticals, enhancing their solubility, stability, and bioavailability, which are crucial for effective drug delivery and therapeutic action.
Used in Drug Delivery Systems:
In the field of drug delivery, Benzyl-PEG7-amino is utilized as a component of systems designed to improve the targeted delivery of therapeutic agents, reduce side effects, and increase patient compliance. Its PEG chain and amino group contribute to the customization of drug carriers for specific applications.
Used in Biomedical Applications:
Benzyl-PEG7-amino is also employed in a range of biomedical applications beyond drug synthesis and delivery. Its biocompatibility and low toxicity make it suitable for use in diagnostic tools, imaging agents, and as a component in the development of biomaterials for tissue engineering and regenerative medicine.
Used in Chemical Conjugation:
Due to the presence of the amino group, Benzyl-PEG7-amino is used for the conjugation of biologically active molecules, such as peptides, proteins, and nucleic acids, to other molecules or surfaces, facilitating the development of new conjugated products with enhanced properties or functionalities.
Used in the Cosmetics Industry:
Benzyl-PEG7-amino may also find application in the cosmetics industry, where its solubility and stability, along with biocompatibility, can be leveraged to improve the performance of cosmetic formulations, such as creams, lotions, and serums, providing enhanced skin hydration and conditioning effects.
Each application of Benzyl-PEG7-amino leverages its unique structural features and properties to contribute to advancements in respective fields, emphasizing its multifaceted utility in modern science and technology.
Check Digit Verification of cas no
The CAS Registry Mumber 868594-43-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,8,5,9 and 4 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 868594-43:
(8*8)+(7*6)+(6*8)+(5*5)+(4*9)+(3*4)+(2*4)+(1*3)=238
238 % 10 = 8
So 868594-43-8 is a valid CAS Registry Number.
868594-43-8Relevant articles and documents
Synthesis of bifunctional integrin-binding peptides containing PEG spacers of defined length for non-viral gene delivery
Pilkington-Miksa, Michael A.,Sarkar, Supti,Writer, Michele J.,Barker, Susie E.,Shamlou, Parviz Ayazi,Hart, Stephen L.,Hailes, Helen C.,Tabor, Alethea B.
experimental part, p. 2900 - 2914 (2009/04/11)
Improving the buffer and serum stability of non-viral gene delivery vectors, and increasing their circulation time in vivo, is an important focus of current research in gene therapy. The most successful strategies to date have involved shielding the complexes with large polydisperse PEG adducts. However, this approach is accompanied by a fall in transfection efficiency. In this paper we describe the solid-phase synthesis of a series of bifunctional peptides bearing short PEG spacers of defined structure as components of lipopolyplex gene delivery vectors. Short, high-yielding routes to a series of PEG-amino acids are described: these PEG-amino acids can be used in varying combinations to afford bifunctional peptides with varying lengths of PEG spacers by using standard solid-phase synthesis techniques. A series of lipopolyplexes were formulated using these bifunctional peptides, and their transfection properties assessed. Dynamic light scattering measurements on the complex with the best transfection properties showed that in phosphate-buffered saline this complex was considerably more stable, and aggregated more slowly, than a complex formulated using a similar peptide lacking the short PEG spacer. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
