868605-87-2

Upstream product

• 690264-31-4 5-(4-chloro-phenyl)-2-ethynyl-pyridine 
• 75793-88-3 6-iodo-4-methylquinolin-2(1H)-one 

Downstream Products

• 868605-89-4 2-bromo-6-[5-(4-chloro-phenyl)-pyridin-2-ylethynyl]-4-methyl-quinoline 
• 868605-88-3 2-chloro-6-[5-(4-chloro-phenyl)-pyridin-2-ylethynyl]-4-methyl-quinoline 

Relevant academic research and scientific papers

Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds

Alkyne compounds of formula I wherein A, B, W, X, Y, Z, R1, and R2 have the meanings given herein, which have MCH-receptor antagonistic activity and are useful for preparing pharmaceutical compositions for the treatment of metabolic disorders and/or eating disorders, particularly obesity and diabetes.

NOVEL ALKYNE COMPOUNDS HAVING AN MCH-ANTAGONISTIC EFFECT AND MEDICAMENTS CONTAINING SAID COMPOUNDS

The invention relates to alkyne compounds of general formula (I), in which groups and residues A, B, W, X, Y, Z, R1 and R2 have the meanings cited in Claim 1. The invention also relates to medicaments containing at least one inventive alkyne. The MCH receptor antagonistic effect renders the inventive medicaments suitable for treating metabolic disorders and/or eating disorders, in particular, obesity and diabetes.