868618-89-7

Upstream product

• 106-45-6 para-thiocresol 
• 185114-94-7 1,2,4,6-Tetra-O-acetyl-3-azido-3-deoxy-α/β-gluco-hexopyranose 
• 27581-57-3 3-azido-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 868618-88-6 p-methylphenyl 2,4,6-tri-O-acetyl-3-azido-3-deoxy-1-thio-β-D-glucopyranoside 
• 98-88-4 benzoyl chloride 

Relevant academic research and scientific papers

An efficient method to synthesize novel 5-O-(6′-modified)-mycaminose 14-membered ketolides

A new and facile procedure was developed to synthesize novel 5-O-(6′-modified)-mycaminose 14-membered ketolides by adopting different protective strategies and comparing various glycosylation conditions. Seven trichloroacetimidate donors which had different types of substituent groups at C-6 position were synthesized to couple with the erythronolide. Nine novel 5-O-(6′-modified)-mycaminose 14-membered ketolides were obtained to verify the utility of the method.

Branched aminoglycosides: Biochemical studies and antibacterial activity of neomycin B derivatives

The C5″-OH group in neomycin B was glycosylated with a variety of mono- and di-saccharides to probe the effect of introduction of additional binding elements on antibacterial activity and interaction with the aminoglycosides modifying enzyme APH(3′)-IIIa.