868632-12-6Relevant academic research and scientific papers
Catechol: A minimal scaffold for non-peptide peptidomimetics of the i + 1 and i + 2 positions of the β-turn of somatostatin
Mowery, Brendan P.,Prasad, Vidya,Kenesky, Craig S.,Angeles, Angie R.,Taylor, Laurie L.,Feng, Jin-Jye,Chen, Wen-Long,Lin, Atsui,Cheng, Fong-Chi,Smith III, Amos B.,Hirschmann, Ralph
, p. 4397 - 4400 (2007/10/03)
The design, synthesis, and evaluation of a series of catechol-based non-peptide peptidomimetics of the peptide hormone somatostatin have been achieved. These ligands comprise the simplest known non-peptide mimetics of the i + 1 and i + 2 positions of the
Synthesis of somatostatin mimetics based on the 1-deoxymannojirimycin scaffold
Gouin, Sebastien G.,Murphy, Paul V.
, p. 8527 - 8532 (2007/10/03)
A novel synthesis of somatostatin mimetics based on the 1-deoxymannojirimycin (DMJ) scaffold has been developed. This involved development of a route suitable for the strategic grafting of pharmacophoric tryptophan and lysine side chains to the nitrogen a
