868659-67-0Relevant academic research and scientific papers
Synthesis of indene derivatives via electrophilic cyclization
Khan, Zulfiqar Ali,Wirth, Thomas
supporting information; experimental part, p. 229 - 231 (2009/06/20)
3-Iodo-1H-indene derivatives are synthesized by iodonium-promoted 5-endo-dig carbocyclization of 2-substituted ethynylmalonates. Various 2-substituted ethynylmalonates bearing aryl-, alkyl-and ether-protected propargyl alcohols were successfully converted
Synthesis of indenes by the transition metal-mediated carboannulation of alkynes
Zhang, Daohua,Liu, Zhijian,Yum, Eul K.,Larock, Richard C.
, p. 251 - 262 (2007/10/03)
The synthesis of highly substituted indenes has been achieved by three different transition metal-mediated methods. The first method involves the palladium-catalyzed carboannulation of internal alkynes. The second method utilizes a two-step approach, which involves first the palladium/copper- catalyzed cross-coupling of terminal alkynes with appropriately functionalized aryl halides, followed by copper-catalyzed intramolecular cyclization. The third method involves intermolecular palladium-catalyzed arylation of the arylalkynes formed in the first step of the second method.
Pd/C-mediated coupling of aryl halides with terminal alkynes in water
Batchu, Venkateswara Rao,Subramanian, Venkataraman,Parasuraman, Karuppasamy,Swamy, Nalivela Kumara,Kumar, Sanjeev,Pal, Manojit
, p. 9869 - 9877 (2007/10/03)
2-Aminoethanol facilitated the alkynylation of aryl halides (Sonogashira reaction) under palladium/charcoal-copper catalysis in water affording a mild and practical method for the synthesis of arylalkynes. A variety of terminal alkynes were coupled with a
