868747-99-3

Usage

Uses

Used in Perfumery and Flavoring Industry:
(E)-3-methyl-4-(p-tolyl)-3-buten-1-ol is used as a fragrance ingredient for its sweet, floral odor, enhancing the sensory experience of various products in the perfumery and flavoring sectors.
Used in Organic Synthesis:
(E)-3-methyl-4-(p-tolyl)-3-buten-1-ol serves as a building block in the synthesis of other organic compounds, contributing to the development of new chemical entities with diverse applications.
Used in Pharmaceutical Research:
(E)-3-methyl-4-(p-tolyl)-3-buten-1-ol is used as a subject of study in pharmaceutical research for its potential anti-inflammatory and antioxidant properties, which could lead to the development of new therapeutic agents.
Safety Precautions:
It is crucial to handle (E)-3-methyl-4-(p-tolyl)-3-buten-1-ol with care, as it may cause skin and eye irritation. Additionally, it poses risks if ingested or inhaled in large quantities, necessitating proper safety measures during its use and storage.

Upstream product

• 106-38-7 para-bromotoluene 
• 29540-83-8 p-tolyl triflate 
• 763-32-6 2-methyl-1-buten-4-ol 

Downstream Products

• 868748-03-2 3-methyl-4-(p-tolyl)-1-butanol 

Relevant academic research and scientific papers

Novel process for preparation of 2,6-dialkyltetralin

The present invention provides a novel process for highly selective preparation of 2,6-dialkyltetralin, a key precursor for 2,6-dimethylnaphthalene (2,6-DMN), which does not require an extra step for purifying various isomers obtained from the conventional processes for 2,6-DMN. The present invention is advantageous to improve the synthetic yield, to simplify the operation and thus to reduce the production cost, since different starting materials and different pathways are exploited and thus the additional steps are not necessary.

Regioselective synthesis of 2,6-dimethyltetralin: Key precursor to 2,6-dimethylnaphthalene

A novel regioselective synthesis for 2,6-dimethyltetralin (2,6-DMT), a key precursor to 2,6-dimethylnaphthalene (2,6-DMN), is described. The synthesis comprises the following three steps; the Heck reaction between commercially available 4-bromotoluene and 3-methyl-3-buten-1-ol, the catalytic reduction of the coupling products, and the acid-catalyzed cyclization of the alcohol intermediate. The process has an advantage over the established processes in that 2,6-DMT is obtained as the only isomer, and the isomerization and/or the complicated separation and purification steps are not required to produce pure 2,6-DMT. 2,6-DMN could be also obtained as a major product depending on the cyclization conditions.