868776-15-2

Upstream product

• 822-36-6 4-methyl-1H-imidazole 
• 403-33-8 methyl 4-flurobenzoate 
• 619-44-3 methyl 4-iodobenzoate 

Downstream Products

• 868776-16-3 ethyl 4-[(2-methoxyethyl)(methyl)amino]benzoate 
• 868776-17-4 4-[(2-methoxyethyl)(methyl)amino]benzoic acid 
• 167758-77-2 (4-(4-methyl-1H-imidazol-1-yl)phenyl)methanol 
• 220462-29-3 4-(4-methyl-1H-imidazol-1-yl)benzoic acid 

Relevant academic research and scientific papers

NITROGEN-CONTAINING HETEROCYCLIC COMPOUND

Provided is a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity, and useful as a prophylactic or therapeutic drug for Alzheimer's disease, schizophrenia, pain, sleep disorder and the like. The present invention relates to a compound represented by the formula wherein ring A is a 4- to 7-membered ring optionally having substituent (s) ; L is -O-, -S-, -SO- or -SO2-; R1 is a C1-6 alkyl group optionally having substituent(s) (provided that when L is -O-, R1 is not a C1-6 alkyl group optionally substituted by halogen atom(s)), or a cyclic group optionally having substituent(s); X1 is -CRa= or -N=; X2 is -CRb= or -N=; X3 is-CRc= or -N=; Ra, Rb and Rc are each a C1-6 alkyl group, C2-6 alkenyl group, C1-6 alkoxy group, C3-6 cycloalkyl group, C3-6 cycloalkoxy group or C6-14 aryl group, each of which optionally having substituent(s), H or halogen, or a salt thereof.

FUSED QUINOLINE DERIVATIVE AND USE THEREOF

The present invention aims at provision of a quinoline derivative having a neurokinin 2 (NK2) receptor antagonistic action and relates to a compound represented by the formula (I) wherein Rl is a hydrogen atom and the like; R2 is a hydrogen atom, a hydrocarbon group optionally having substituent(s) and the like; R3 is unsubstituted (i.e., absence), a hydrogen atom and the like; R4 and R5 are the same or different and each is a hydrogen atom, a hydrocarbon group optionally having substituent(s), and the like; R6is (cyclic group optionally having substituent(s)) -carbonyl, and the like; R7, R8,R9 and R10 are the same or different and each is a hydrogen atom, halogen and the like; or R7and R8,R8 and R9,and R9 and R10 may form a ring together with the adjacent carbon atoms; n is an integer of 1 to 5; --- represents unsubstituted (i.e., absence) or a single bond; and --- represents a single bond or a double bond, or a salt thereof, and the like.