86882-33-9

Upstream product

• 86882-01-1 4-Methyl-2-(2-p-tolyl-2,3-dihydro-benzo[b][1,4]thiazepin-4-yl)-phenol 
• 123716-01-8 4,5'-Dimethyl-2'-hydroxy-chalkon 
• 137-07-5 2-amino-benzenethiol 

Relevant academic research and scientific papers

Synthesis of 2,4-Diaryl-2,3-dihydro-1,5-benzothiazepines & their 1,1-Dioxides as antibacterial Agents

o-Aminothiophenol reacts with chalkones (I) in methanol-acetic acid to give 3-(2-aminophenylmercapto)-3-arylpropiophenones (II) which immediately undergo cyclization in situ to give 2,4-diaryl-2,3-dihydro-1,5-benzothiazepines (IIIa).Compounds IIIa are easily oxidised to the corresponding 1,1-dioxides (IV) by H2O2 (30percent) in gl. acetic acid.A few compunds have been screened for their antibacterial activity against S. aureus, S. typhi., V.Comma and E. coli.