868944-63-2

Upstream product

• 556-56-9 allyl iodid 
• 158724-94-8 (S)-3-(2-Benzyloxy-acetyl)-4-isopropyl-1-phenyl-imidazolidin-2-one 
• 19810-31-2 Benzyloxyacetyl chloride 
• 138522-39-1 (4S)-4-(1-methylethyl)-1-phenyl-2-imidazolidinone 

Relevant academic research and scientific papers

Diastereoselective alkylation of chiral 2-imidazolidinone glycolates: Asymmetric synthesis of α-hydroxy carboxylic acids

Sodium enolates of chiral 2-imidazolidinone glycolates reacted with alkyl halides to produce α-alkylated products with high diastereoselectivities, which were readily removed by simple alkaline hydrolysis and were converted to the protected α-hydroxy carboxylic acids. The new stereogenic center was assigned the (R)-configuration by comparison with known compounds.