869002-62-0

Upstream product

• 253453-91-7 2-chloro-1-methyl-1H-imidazole 
• 68-12-2 N,N-dimethyl-formamide 
• 107-31-3 Methyl formate 

Downstream Products

• 869002-70-0 (3-fluoro-phenyl)-(2-chloro-3-methyl-3H-imidazol-4-yl)-methanol 

Relevant academic research and scientific papers

Lewis basicity modulation of N-heterocycles: A key for successful cross-metathesis

Cross-metathesis involving N-heteroaromatic olefinic derivatives is disclosed. The introduction of an appropriate substituent on the heteroaromatic ring decreases the Lewis basicity of the nitrogen atom, thus preventing the deactivation of the ruthenium-centered catalyst. The reaction is quite general in terms of both N-heterocycles and olefinic partners.

Scalable synthesis of imidazole derivatives

Imidazole derivatives, compositions containing them, methods of preparing them, including regioselective scale-up synthetic methods, and methods of using them.