869059-97-2Relevant academic research and scientific papers
Synthesis of 3-amino-3,4-dihydro-1H-quinolin-2-ones through regioselective palladium-catalyzed intramolecular cyclization
Hallé, Fran?ois,Van der Poorten, Olivier,Doebelin, Christelle,Niederst, Marie,Schneider, Séverine,Schmitt, Martine,Ballet, Steven,Bihel, Frédéric
, p. 1547 - 1550 (2016)
In this Letter we explored the regioselective cyclization of 2-bromophenylalanine derivatives to access enantiopure dihydroquinolinones via an intramolecular regioselective Buchwald–Hartwig cyclization using Pd2(dba)3/XPhos as a catalytic system in the presence of BTPP as organic base. This procedure represents a promising strategy for the direct synthesis of bridged Phe-Xaa dipeptides.
LXR receptor modulators
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Page/Page column 12-13, (2010/11/27)
Benzenesulfonamide derivative compounds corresponding to the general formula (I): and their pharmaceutically acceptable addition salts; a process for preparation of such compounds; pharmaceutical compositions containing such compounds, and the use of such
