869118-91-2

Basic information

• Product Name: 4-bromo-5-(diphenylphosphino)-2,6-dimethoxypyrimidine
• Synonyms: 4-bromo-5-(diphenylphosphino)-2,6-dimethoxypyrimidine
• CAS NO: 869118-91-2
• Molecular Weight: 403.215
• Mol File: 869118-91-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-bromo-5-(diphenylphosphino)-2,6-dimethoxypyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-5-(diphenylphosphino)-2,6-dimethoxypyrimidine(869118-91-2)
• EPA Substance Registry System: 4-bromo-5-(diphenylphosphino)-2,6-dimethoxypyrimidine(869118-91-2)

Safety Data

• Hazardous Substances Data: 869118-91-2(Hazardous Substances Data)

Upstream product

• 56686-16-9 5-bromo-2,4-dimethoxypyrimidine 
• 1079-66-9 chloro-diphenylphosphine 
• 108-18-9 diisopropylamine 

Downstream Products

• 869118-92-3 4-bromo-5-(diphenylphosphinoyl)-2,6-dimethoxypyrimidine 

Relevant articles and documents

PHARMACEUTICAL COMPOSITIONS

The present invention provides bipyrimidinyl diphosphine compounds of the formula, formula (I) wherein R is optionally substituted alkyl, cycloalkyl, aryl or heteroaryl; R' and R" are independently optionally substituted alkyl, cycloalkyl, aryl or heteroaryl; or an enantiomer thereof; or an enantiomeric mixture thereof. The compounds of the formula (I) are chiral atropisomeric bipyrimidinyl diphosphine compounds and, thus, may be employed as ligands to generate chiral transition metal catalysts which may be applied in a variety of asymmetric reactions, e.g., in palladium catalyzed asymmetric allylic substitution reactions. The compounds of the present invention are easily accessible a in high enantiomeric purity according to the methods disclosed herein.