869209-18-7

Upstream product

• 686775-60-0 ethyl (Z)-[4-(3-biphenyl-4-yl-3-iodoprop-2-enylsulfanyl)-2-methylphenoxy]acetate 
• 768-60-5 4-methoxyphenylacetylen 
• 288101-05-3 (Z)-3-biphenyl-4-yl-3-iodoprop-2-en-1-ol 
• 210885-00-0 3-([1,1'-biphenyl]-4-yl)prop-2-yn-1-ol 
• 3218-36-8 4-Phenylbenzaldehyde 

Relevant academic research and scientific papers

Novel selective PPARδ agonists: Optimization of activity by modification of alkynylallylic moiety

Y-shaped molecules bearing alkynylallylic moieties were found to be potent and selective PPARδ activators. The alkynylallylic moiety was synthesized from alkyn-1-ols by hydroalumination followed by a cross-coupling reaction. Series of active compounds 6 w

NOVEL COMPOUNDS, THEIR PREPARATION AND USE

Novel compounds of the general formula (I), in which the variables are as defined in claim 1, the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compound