869222-68-4 Usage
Uses
Used in Pharmaceutical Industry:
(E)-5-[3-(TRIFLUOROACETAMIDO)-1-PROPENYL]URIDINE is used as a reactant/reagent for the preparation of modified nucleosides, nucleotides, and nucleic acids. These modified molecules are essential for the development of novel therapeutic agents and diagnostic tools, particularly in the area of human granulocyte-colony stimulating factor (G-CSF) modified mRNA-induced cell proliferation.
Used in Biotechnology Industry:
In the biotechnology sector, (E)-5-[3-(TRIFLUOROACETAMIDO)-1-PROPENYL]URIDINE is utilized as a reactant/reagent for the synthesis of modified nucleic acids that can be employed in various applications, such as gene editing, gene therapy, and the development of vaccines. Its role in these applications is vital for enhancing the efficiency and effectiveness of these technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 869222-68-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,9,2,2 and 2 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 869222-68:
(8*8)+(7*6)+(6*9)+(5*2)+(4*2)+(3*2)+(2*6)+(1*8)=204
204 % 10 = 4
So 869222-68-4 is a valid CAS Registry Number.
869222-68-4Relevant academic research and scientific papers
Synthesis of pyrophosphates for in vitro selection of catalytic RNA molecules
Kim, Hyo-Joong,Kim, Myong Jung,Karalkar, Nilesh,Hutter, Daniel,Benner, Steven A.
, p. 43 - 56 (2008/09/18)
Reported here are synthetic routes to pyrophosphates linking riboflavin with various nucleosides. The focus is on a flavin-uracil dinucleotide having a biotin tag on the uracil, a molecule that has potential value in the selection of RNA enzymes that catalyze the template-directed polymerization of RNA in the 3′-to-5′ direction, which is the direction opposite that catalyzed by standard protein polymerases. Two detailed procedures are presented to prepare this new compound, as well as one procedure to prepare the new flavin-2,6-diaminopurine dinucleotide. Copyright Taylor & Francis Group, LLC.
