869278-52-4 Usage
Type
Benzyl ester derivative of a thienopyridine compound
Functional groups
Contains an amino group, a carbamoyl group, and a carboxylic acid group
Thienopyridine compounds
Known for potential pharmaceutical properties such as antitumor, anti-inflammatory, and antiviral effects
Benzyl ester form
Indicates presence of a benzyl group attached to the carboxylic acid functional group
Potential uses
Further research needed to fully understand potential uses and effects of compound
Check Digit Verification of cas no
The CAS Registry Mumber 869278-52-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,9,2,7 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 869278-52:
(8*8)+(7*6)+(6*9)+(5*2)+(4*7)+(3*8)+(2*5)+(1*2)=234
234 % 10 = 4
So 869278-52-4 is a valid CAS Registry Number.
869278-52-4Relevant academic research and scientific papers
Parallel synthesis and biological evaluation of 5,6,7,8- tetrahydrobenzothieno[2,3-d]pyrimidin-4(3H)-one cytotoxic agents selective for p21-deficient cells
Jennings, Lee D.,Kincaid, Scott L.,Wang, Yanong D.,Krishnamurthy, Girija,Beyer, Carl F.,McGinnis, John P.,Miranda, Miriam,Discafani, Carolyn M.,Rabindran, Sridhar K.
, p. 4731 - 4735 (2007/10/03)
A novel series of inhibitors of cancer cell proliferation, selective against p21 cell cycle checkpoint-disrupted cells vs. cells with intact p21 checkpoint, were identified by high-throughput screening. Optimization of both ends of the lead molecule to improve potency, using parallel synthesis and iterative design, is described. The 2-(1,4-dibenzodioxane)-substituted derivative 14 was identified as a highly selective and potent agent displaying an IC50 of 91 nM in the p21-deficient cell line.
