869287-42-3Relevant academic research and scientific papers
New approach to the practical synthesis of tri- or tetrasubstituted pyrimidine derivatives: A four-component coupling reaction from a functionalized silane, two types of aromatic nitriles, and acetals
Sakai, Norio,Aoki, Youichi,Sasada, Toshiaki,Konakahara, Takeo
, p. 4705 - 4708 (2005)
(Chemical Equation Presented) A new approach to the synthesis of tri- or tetrasubstituted pyrimidines by a four-component coupling reaction using a functionalized silane, two types of aromatic nitriles, and an acetal is described. The efficient transforma
Synthesis of tri-or tetrasubstituted pyrimidine derivatives through the [5+1] annulation of enamidines with either N,N-dimethylformamide dialkyl acetals or orthoesters and their application in a ring transformation of pyrimidines to pyrido[2,3-d]pyrimidin
Sasada, Toshiaki,Aoki, Youichi,Ikeda, Reiko,Sakai, Norio,Konakahara, Takeo
supporting information; experimental part, p. 9385 - 9394 (2011/10/02)
The [5+1] annulation of enamidines, which were prepared from functionalized silanes, organolithium compounds and two nitriles, with N,N-dimethylformamide dialkyl acetals as the C1 unit is described, leading to the synthesis of tri- and tetrasubstituted py
