869287-54-7Relevant academic research and scientific papers
Studies towards topical selective β2-adrenoceptor agonists with a long duration of action
Bouyssou, Thierry,Rudolf, Klaus,Hoenke, Christoph,Lustenberger, Philipp,Schnapp, Andreas,Konetzki, Ingo
scheme or table, p. 5237 - 5240 (2010/03/31)
β2-Adrenoceptor agonists with basic and acidic groups attached via an alkyl linker to the phenyl ethanolamine core were prepared and investigated in vitro and in vivo. The compounds exhibited a high potency in a functional cellular assay and a bronchoprotective effect in a guinea pig model which lasted over the complete study period of 5 h.
Novel long acting bronchodilators for the treatment of respiratory diseases
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Page/Page column 11, (2010/02/14)
The invention relates to compounds of general formula 1 wherein n, A, B, D, L, R1, R2, R3 and R4 may have the meanings given in the claims and in the specification, processes for preparing them, and their use as
NOVEL SUSTAINED-ACTION BRONCHODILATING AGENTS FOR USE IN THE TREATMENT OF RESPIRATORY DISEASES
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Page/Page column 23, (2010/02/14)
The invention relates to the compounds of general formula (1), wherein the groups n, A, B, D, L, R1, R2, R3 and R4 are defined as in the claims and in the description, and to methods for producing the same. The invention also relates to the use of these compounds as drugs, especially as drugs for use in the treatment of respiratory diseases.
