86932-95-8Relevant academic research and scientific papers
Discovery of new chemical entities as potential leads against Mycobacterium tuberculosis
Lu, Xiaoyun,Tang, Jian,Liu, Zhiyong,Li, Minke,Zhang, Tianyu,Zhang, Xiantao,Ding, Ke
supporting information, p. 5916 - 5919 (2016/12/06)
A series of biheterocyclic (1H-indole, benzofuran, pyrazolo[1,5-a]pyrimidine, pyrazolo[1,5-a]pyrimidin-5(4H)-one, imidazo[2,1-b]thiazole and pyrazolo[5,1-b]thiazole) derivatives were synthesized and evaluated for their anti-tubercular activities. The imid
3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES
-
Page/Page column 41, (2010/02/17)
The invention relates to 3-aza-bicyclo[3.1.0]hexane derivatives of formula (I) wherein A, B, n, X, and R1 are as described in the description, and salts thereof, and their use as orexin receptor antagonists.
TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES
-
Page/Page column 77, (2009/03/07)
The invention relates to novel trans-3-aza-bicyclo[3.1.0]hexane derivatives of formula (I), wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.
RESEARCH ON HETEROCYCLIC COMPOUNDS. XIV. - Imidazothiazole and imidazobenzothiazole derivatives : synthesis and antiinflammatory activity.
Abignente, E.,Caprariis, P. De,Sacchi, A.,Marmo, E.,Berrino, L.,Matera, M. G.
, p. 533 - 545 (2007/10/02)
A group of ethyl 6-methylimidazothiazole-5-carboxylates and 2-methylimidazobenzothiazole-3-carboxylates was prepared by reaction of ethyl 2-chloroacetoacetate with some 2-aminothiazoles and 2-aminobenzothiazoles, respectively.Such reactions may sometimes afford a side product which was isolated and characterized.The ethyl esters were then converted into the corresponding acids by hydrolysis.Three of these acids were evaluated for antiinflammatory, analgesic, and antipyretic activities, as well as for ulcerogenic potential.
