1603-91-4

Basic information

• Product Name: 2-Amino-4-methylthiazole
• Synonyms: Nomortiroide;Normotiroide;Thiazole, 2-amino-4-methyl-;2-Amino-4-methylthiazole, 98+%;4-Methylthiazole-2-amine;2-AMino-4-Methylthiazole, 98% 25GR;AMino-4-Methylthiazole;Thiazole, 2-aMino-4-Methyl- (6CI,7CI,8CI)
• CAS NO: 1603-91-4
• Molecular Formula: C₄H₆N₂S
• Molecular Weight: 114.17
• EINECS: 216-505-6
• Product Categories: FINE Chemical & INTERMEDIATES;Amines;blocks;Thiazoles;Thiazoles, Isothiazoles &Benzothiazoles;Thiazoles, Isothiazoles & Benzothiazoles;Building Blocks;Heterocyclic Building Blocks
• Mol File: 1603-91-4.mol
• Article Data: 34

Chemical Properties

• Melting Point: 44-47 °C(lit.)
• Boiling Point: 231-232 °C(lit.)
• Flash Point: >230 °F
• Appearance: /solid
• Density: 1.176 (estimate)
• Vapor Pressure: 0.059mmHg at 25°C
• Refractive Index: 1.5000 (estimate)
• Storage Temp.: Refrigerator
• Solubility: soluble in Methanol
• PKA: 5.36±0.10(Predicted)
• Water Solubility: soluble
• Sensitive: Hygroscopic
• Merck: 14,450
• BRN: 107890
• CAS DataBase Reference: 2-Amino-4-methylthiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-4-methylthiazole(1603-91-4)
• EPA Substance Registry System: 2-Amino-4-methylthiazole(1603-91-4)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-36/37-22-20/21/22
• Safety Statements: 26-36-39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 1603-91-4(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystal powde

InChI:InChI=1/C4H6N2S/c1-3-2-7-4(5)6-3/h2H,1H3,(H2,5,6)

Upstream product

• 3029-48-9 thiocyanoacetone 
• 626-34-6 ethyl aminocrotonate 
• 89416-37-5 acetic acid-(α,β-dichloro-isopropyl ester) 
• 17356-08-0 thiourea 
• 854667-12-2 acetic acid-(α,β-dibromo-isopropyl ester) 
• 1071-86-9 bis(formamidine)disulphide dihydrobromide 
• 67-64-1 acetone 
• 78-95-5 chloroacetone 
• 127-09-3 sodium acetate 
• 64-17-5 ethanol 
• 7732-18-5 water 
• 60-29-7 diethyl ether 
• 7664-41-7 ammonia 
• 287475-98-3 1,2-bis(4-methylthiazol-2-yl)hydrazine 

Downstream Products

• 98484-42-5 2-(2-hydroxyethylamino)-4-methylthiazole 
• 42574-75-4 N-(4-methyl-thiazol-2-yl)-maleamic acid 
• 37469-37-7 phenylpropynoic acid 4-methyl-thiazol-2-ylamide 
• 23430-05-9 3-methyl-7-phenyl-thiazolo[3,2-a]pyrimidin-5-one 
• 32278-43-6 3-methyl-5-phenyl-thiazolo[3,2-a]pyrimidin-7-one 
• 16131-76-3 3-(4-methyl-thiazol-2-yl)-3-aza-bicyclo[3.2.0]heptane-2,4-dione 
• 19691-92-0 N-(4-Methyl-2-thiazolyl)-1,8-naphthalimid 
• 57332-95-3 ethyl 3-methylimidazo<2,1-b>thiazole-6-carboxylate 
• 41346-47-8 N,N-bis-(2-chloro-ethyl)-N'-(4-methyl-thiazol-2-yl)-phosphorodiamidic acid 2-methoxy-phenyl ester 
• 92697-08-0 6-(4-bromo-phenyl)-3,5-dimethyl-imidazo[2,1-b]thiazole 
• 75793-01-0 2,5-dichloro-3,6-bis-(4-methyl-thiazol-2-ylamino)-[1,4]benzoquinone 
• 53995-67-8 2,3-diamino-4-methyl-thiazolium; 2,4,6-trimethyl-benzenesulfonate 
• 782424-38-8 3-Aethyl-2-imino-4-methyl-4-thiazolin 
• 50772-53-7 2-chloro-N-(4-methylthiazol-2-yl)acetamide 

Related news

Spectroscopic and spectrophotometric studies on hydrogen bonded charge transfer complex of 2-Amino-4-methylthiazole (cas 1603-91-4) with chloranilic acid at different temperatures07/17/2019

The synthesized hydrogen bonded charge transfer (CT) complex between 2-amino-4-methylthiazole (AMT) and chloranilic acid (CLA) was characterized using various spectral techniques such as UV–visible, FTIR, 1H NMR, ESI-MS, P-XRD and TG/DTA analysis. The CT complexes act as an intermediate in a va...detailed

Relevant articles and documents

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Inhibitory effect of 2-aminothiazole derivatives in oxidation reactions

The kinetics and mechanism of inhibitory effect of 2-aminothiazole derivatives in the radical-initiated oxidation of cumene were studied.

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Biocidal and anticorrosive effect of 2-aminothiazole derivatives used as additives to jet fuels

The effect of 2-aminothiazole derivatives on the biological resistance and corrosion activity of jet fuels was studied under conditions of water condensation.

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Synthesis and photoelectric properties of IrIIIcomplexes using fluorobenzylimidazole[2,1-b]thiazole derivatives as primary ligands

3-Methyl-6-(3,5-difluorophenyl)imidazo[2,1-b]thiazole (mdfpit) and 3-methyl-6-(3,4,5-trifluorophenyl)imidazo[2,1-b]thiazole (mtfpit) were easily prepared from thiourea, acetone, and 3,5-difluorobenzoyl bromide or 3,4,5-trifluorobenzoyl bromide. These were used as primary ligands to synthesize twelve phosphorescent IrIIIcomplexes with picolinic acid (pic), isoquinoline-3-carboxylic acid (3-IQA), quinoline-2-carboxylic acid (2-QA), 2-(pyridin-2-yl)phenol (2-ylppy), 2-(2,4-difluorophenyl)pyridine (dfppy), and pyridine-2-sulfonic acid (2-sappy) as auxiliary ligands. Their structures, photoluminescence, and electrochemical properties were investigated. Upon introducing more fluorine atoms into the benzene ring of the primary ligand, the thermal stability, photoluminescence quantum yield (PLQY), LUMO energy level, and luminous efficiency of the resulting IrIIIcomplexes are significantly improved, and the photoluminescence emission spectra are blue-shifted. Their maximum emission wavelengths are present in the range of 517-618 nm, and the luminous colors span from the green to red light region. Using the synthesized IrIIIcomplexes as emitters, LED chips based on InGaN chip excitation were developed, which showed good performances. Among all LEDs, the PLQY of the (mtfpmt)2Ir(pic) based LED is 58.4%, and the luminous efficiency is as high as 17.11 lm W?1; the luminous efficiency of the (mdfpmt)2Ir(2-QA) based LED is 3.41 lm W?1with CIE coordinates of 0.60 and 0.38, which are very similar to the saturated standard red light emission. The results demonstrate the potential of the studied IrIIIcomplexes as candidates for LED materials.

Iridium complex with 3-methyl-6-phenylimidazole[2, 1-b]thiazole derivative as main ligand

The invention discloses ten iridium (III) complexes, which are characterized in that: the main ligands of the complexes are 3-methyl-6-phenylimidazole[2, 1-b]thiazole (mpmt) and 3-methyl-6-(4-(trifluoromethyl)phenyl)imidazo[2, 1-b]thiazole (mtfpmt) respectively, and the auxiliary ligands are 2-picolinic acid (pic), isoquinoline-3-formic acid (3-IQA), quinoline-2-carboxylic acid (2-QA), 1-phenylisoquinoline (piq) and 2-(2, 4-difluorophenyl)pyridine (dfppy) respectively, and the structures are shown as the specification, wherein the definition of X substituent group is selected from one of twogroups of complexes. Light-emitting diodes prepared from the complexes have a maximum emission wavelength of 540.3-627.8nm and light-emitting efficiency of 0.18-3.01 lm.W, wherein (mtfpmt)2Ir(pic)emits pure green light, and (mpmt)2Ir(2-QA) emits pure red light, and the color purity is high. near white light can be obtained after mixing of the light emitted by (mtfpmt)2Ir(dfppy) and a galliumnitride chip, therefore the complexes can be used for making of white light LED. Excellent performance of the devices indicates that the complexes have application value in preparation of organic photoluminescent and electroluminescent devices. The invention discloses a structure and a synthesis method of the complexes, and a structure and a preparation method of organic photoluminescent devices.