869366-10-9 Usage
Uses
Used in Pharmaceutical Research:
(E)-8-chloro-1-(2,6-difluorophenyl)-4-((diMethylaMino)Methylene)-3H-benzo[c]azepin-5(4H)-one is used as a research reagent for the development of new drugs targeting neurological and psychiatric disorders. Its unique chemical structure and properties make it a valuable tool in the design and synthesis of novel therapeutic agents.
Used in Organic Synthesis:
In the field of organic chemistry, (E)-8-chloro-1-(2,6-difluorophenyl)-4-((diMethylaMino)Methylene)-3H-benzo[c]azepin-5(4H)-one serves as an intermediate in the synthesis of various complex organic molecules. Its versatile structure allows for further functionalization and modification, enabling the creation of a wide range of compounds with diverse applications.
Used in Scientific Studies:
(E)-8-chloro-1-(2,6-difluorophenyl)-4-((diMethylaMino)Methylene)-3H-benzo[c]azepin-5(4H)-one is also employed in scientific research to investigate its pharmacological properties and potential therapeutic uses. Studies on (E)-8-chloro-1-(2,6-difluorophenyl)-4-((diMethylaMino)Methylene)-3H-benzo[c]azepin-5(4H)-one contribute to the understanding of its interactions with biological systems and may lead to the discovery of new treatment options for various conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 869366-10-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,9,3,6 and 6 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 869366-10:
(8*8)+(7*6)+(6*9)+(5*3)+(4*6)+(3*6)+(2*1)+(1*0)=219
219 % 10 = 9
So 869366-10-9 is a valid CAS Registry Number.
869366-10-9Relevant articles and documents
MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors
Sells, Todd B.,Chau, Ryan,Ecsedy, Jeffrey A.,Gershman, Rachel E.,Hoar, Kara,Huck, Jessica,Janowick, David A.,Kadambi, Vivek J.,Leroy, Patrick J.,Stirling, Matthew,Stroud, Stephen G.,Vos, Tricia J.,Weatherhead, Gabriel S.,Wysong, Deborah R.,Zhang, Mengkun,Balani, Suresh K.,Bolen, Joseph B.,Manfredi, Mark G.,Claiborne, Christopher F.
, p. 630 - 634 (2015/06/30)
The Aurora kinases are essential for cell mitosis, and the dysregulation of Aurora A and B have been linked to the etiology of human cancers. Investigational agents MLN8054 (8) and alisertib (MLN8237, 10) have been identified as high affinity, selective,