86941-39-1Relevant academic research and scientific papers
NOVEL HEPATITIS C VIRUS INHIBITORS
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Page/Page column 38, (2013/07/05)
The invention provides compounds of formula (I): wherein Rings A and A' are independently 5-membered optionally substituted aromatic heterocycles; Q is C(=O)NR1R1' or formula U is C(R4)2, O, S, S(=O)2, C(R4)2C(R4)2, CH2O, OCH2, CH2S, SCH2, CH2S(=O)2, S(=O)CH2 or C=C(Ru )2; X is CH2, CHR12, CR12R12, O, S, S(=O)2 or NRx; m is 0, 1, 2 or 3; n is 0, 1, 2 or 3; the other variables are as defined in the claims, which are of use in the treatment or prophylaxis of hepatitis C virus infection, and related aspects.
Asymmetric α-substituted phenethylamines. II. The enantioselective synthesis of 1-aryl-2-phenylethylamines from L- and D-amino acids by means of 1,3-asymmetric induction
Suzuki,Takahashi
, p. 31 - 40 (2007/10/02)
Optically pure (1S, 1'S)-1-aryl-N-(1'-alkyl-2'-hydroxyethyl)-2-phenylethylamines were synthesized from L-alanine, L-leucine, and L-isoleucine via (S)-2-aminoalkanols and (E)-(S)-N-(1-alkyl-2-hydroxyethyl)arylmethylideneamines. On the other hand, the amine
