869487-59-2Relevant academic research and scientific papers
Diastereoselective synthesis of 1,2-diamines by palladium catalyzed aza-Claisen rearrangement
Gonda,Helland,Ernst,Bellus
, p. 729 - 733 (2007/10/02)
In the thermal rearrangement of allylic trichloroacetimidates 6, no 1,2-asymmetric induction can be observed. Palladium(II) catalyzed, hoever, the rearrangement takes place at 25°C and yields diastereoselective (de ≥ 98%) the anti-1,2-diamines 7. The ally
