869544-06-9

Upstream product

• 617-04-9 (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol 
• 194149-26-3 methyl 2,3:4,6-di-O-benzylidene-α-D-mannopyranoside 
• 63598-31-2 methyl 4,6-O-(R)-benzylidene-2-deoxy-α-D-erythrohexopyranosid-3-ulose 
• 67-56-1 methanol 
• 130781-44-1 methyl 4-O-benzoyl-6-bromo-2,6-dideoxy-α-D-erythro-hexopyranosid-3-ulose 
• 149-73-5 trimethyl orthoformate 
• 869544-01-4 1,5-anhydro-4-O-benzoyl-6-bromo-2,6-dideoxy-α-D-erythro-hex-1-en-3-ulose 

Downstream Products

• 869544-09-2 methyl 4-O-benzoyl-6-cyano-2,6-dideoxy-α-D-erythro-hex-3-ulopyranoside dimethyl ketal 

Relevant academic research and scientific papers

Synthesis of N-acylated 7-amino-2,6,7-trideoxy-D-erythroheptopyranosides from methyl α-D-mannoside

Hexopyranoside methyl α-d-mannoside (8) was homologated to yield 7-(acylamino)-2,6,7-trideoxy-heptopyranosides 19-26. A crucial reaction step is the radical cleavage of benzylidene derivative 10 to obtain bromide 11. Since nucleophilic substitution of 11