869631-24-3Relevant academic research and scientific papers
Combined C-H functionalization/C-N bond formation route to carbazoles
Tsang, W. C. Peter,Zheng, Nan,Buchwald, Stephen L.
, p. 14560 - 14561 (2005)
A new method in which a series of substituted carbazoles is efficiently produced by the combination of an amide and an arene is described. The key feature of this method is the palladium-catalyzed tandem directed C-H functionalization and amide arylation. The method tolerates substitution on either ring of the biaryl amide substrates, and the products can be assembled in a simple two-step protocol from readily available reagents. The Pd(0) species generated are reoxidized to Pd(II) in the presence of Cu(OAc)2 and an atmosphere of oxygen. Copyright
