869658-19-5Relevant academic research and scientific papers
AZABICYCLO COMPOUND, MATRIX METALLOPROTEASE INHIBITOR, AND SKIN PREPARATION
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Page 25, (2008/06/13)
An azabicyclo compound (I) or a salt thereof in accordance with the present invention has an excellent inhibiting action on matrix metalloproteases (MMPs) activity, and is useful for pharmaceutical, cosmetic and skin external compositions. wherein R is H,
Bridged bicyclic vasopressin receptor antagonists with V2-selective or dual V1a/V2 activity
Dyatkin, Alexey B.,Hoekstra, William J.,Hlasta, Dennis J.,Andrade-Gordon, Patricia,De Garavilla, Lawrence,Demarest, Keith T.,Gunnet, Joseph W.,Hageman, William,Look, Richard,Maryanoff, Bruce E.
, p. 3081 - 3084 (2007/10/03)
The synthesis and biological testing of a novel series of nonpeptide vasopressin receptor antagonists, containing a bridged bicyclic nucleus, are reported. Variation of substituents (R1-R3) in general formula 3, and the configuration
REACTION D'AZA-DIELS-ALDER DIASTEREOSELECTIVE: UTILISATION DE LA 1-PHENYLETHYL IMINE DE GLYOXYLATE D'ALKYLE POUR LA SYNTHESES DE DERIVES D'α-AMINO ACIDES CYCLIQUES
Abraham, Herve,Stella, Lucien
, p. 9707 - 9718 (2007/10/02)
The use of trifluoroacetic acid-boron trifluoride combination is highly effective in dichloromethane for the activation of 1-phenylethylimine of methyl or ethyl glyoxylates as heterodienophiles in Diels-Alder cycloaddition reactions with a series of conju
